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2018-2019

Eleventh round (2018) – supported studies

Mr. J. Kuiper, PhD Shooting the Messenger
Targeting ERAPs to combat Uveitis
Mrs. Prof. J.H. De Boer, PhD
Multifocal electroretinogram abnormalities in inflammatory macular edema
Mr. Prof. G.P.M. Luyten, PhD
BAP1 predisposition syndrome in familial uveal melanoma
Mrs E. Kiliç, PhD, MD
Spliceosome inhibitors as a therapeutic option for patients with a somatic SF3B1 mutation?
Mr. H.A. Freitas Alves
PILOT – A preclinical vision testing street for rodents
Mr. C.J.F. Boon, MD, PhD, FEBOphth
Stress, steroids, and the eye: unravelling the pathogenesis of central serous chorioretinopathy
Mr G. Melles, PhD, MD
Long-term evaluation of clinical outcome and complications after Bowman layer transplantation for progressive advanced keratoconus
Mrs. J. Ossewaarde-van Norel, PhD and mr. R. van Leeuwen, PhD Determinants and consequences of Bruch’s Membrane calcification in Pseudoxanthoma Elasticum
Mr. S. van der Stigchel, PhD
PILOT – Eye hear you: Improving auditory perception in blind individuals through the deployment of eye-movements
Mrs S. Roosing, PhD
PILOT – A long-read whole genome sequencing approach to unravel the genetic cause in inherited retinal dystrophies
Mrs. S. Micheal, PhD
PILOT – Identification of genetic causes of congenital cataract using sequencing technologies
Mr. T.T.J.M. Berendschot, PhD
Multispectral imaging for improved glaucoma detection and diagnosis
Mrs. R.M.A. van Nispen, PhD
PILOT – A new Patient Reported Outcome Measure (PROM) to assess anti-VEGF treatment in retinal exudative disease: the Dutch Impact of Visual Impairment profile Computer Adaptive Test (IVI-CAT). tissue screening and harvesting
Mrs. Prof. A.I. den Hollander, PhD
Monitoring oxidative stress in patients with age-related macular degeneration
Mrs. S.M.R. Jonker, MD en Mr. C.J.F. Bertens, M.Sc., B.A.Sc.
Molecular background of endothelial cell loss in patients with phakic intraocular lenses: a tear and aqueous humour study
Mrs. Prof. M.J. Jager, PhD
Contribution of pigmentation to the development of intraocular melanoma
Mr. R.W.J. Collin, PhD
Splicing modulation therapy for recurrent ABCA4 mutations underlying Stargardt disease
Mr. Prof. R.M.M.A. Nuijts, PhD
Efficiency and underlying molecular mechanisms of anti-inflammation treatment in keratoconus patients
Mr. T.G.M.F. Gorgels, PhD
Glaucoma-on-a-chip: an in vitro model for glaucoma drug discovery and precision medicine
Mr. R.O. Schlingemann, Prof., PhD, MD and Mrs. I. Klaassen, PhD
Novel targets in tip cells for anti-angiogenesis in exudative AMD
Mr. W.D. Ramdas, MD, PhD and Mrs. A.A.H.J. Thiadens, MD, PhD Nutrigenomics of open-angle glaucoma in different ethnicities
Mrs. A.I. Iglesias, PhD
RNA-sequencing of myopia zebrafish models
Prof. R.M.M.A. Nuijts, PhD
Collagen cross-linking by near infrared illumination (NIR) of Bacteriochlorophyll derivatives for the treatment of infectious keratitis: safety, efficacy and mechanisms of action
Mrs. M.A. Meester-Smoor, PhD
Why is good cholesterol bad for AMD?
Mr. R.J. Lebbink, PhD
In vivo inactivation of HSV-1 by CRISPR/Cas9-mediated genome mutagenesis: a cure for herpes keratitis?
Mrs. Prof. C.C.W. Klaver, PhD
RetinaNL Reading Center

Twelfth round (2019) – supported studies

Prof. C.B. Hoyng, PhD & Mrs. Prof. A.I. den Hollander, PhD
Towards treatment of central areolar choroidal dystrophy
Mrs. E. Kiliç, PhD, MD
PILOT – Unravelling the multifactorial role of BAP1 mutations in UM metastasis
Mrs. R. Kalmann, PhD
Prediction of therapeutic effect of steroids and the risk of recurrence in patients with inflammatory orbital disease via a blood test
Mr. J. Wijnholds, PhD
Development of novel gene editing techniques for retinal disease
Mr. Prof. C.J.F. Boon, MD, PhD, FEBOphth & Mrs. M. Talib, MD
PILOT – CRB1-associated retinal dystrophies: towards gene therapy
Mr. W.D. Ramdas, MD, PhD
The way towards neuroprotective modalities against glaucoma
Mrs. S. Yzer, PhD
Caucasian high and pathologic myopia: a clinical, genetic and epidemiological study
Mr. J.D. van Buul, PhD
Endothelial integrity to the max: corneal repair
Mr. E. van Wijk, PhD & Mr. E. de Vrieze, PhD
Pre-clinical development of a minigene augmentation therapy for the future treatment of USH2C-associated retinitis pigmentosa
Mr. A. Garanto, PhD
Therapeutic genome editing for ABCA4-associated Stargardt disease
Mrs. A.A.H.J. Thiadens, PhD, MD
Getting ready for gene therapy: gene finding and clinical management of cone dystrophies
Mr. Prof. F.W. Cornelissen, PhD
GazeJoy: Assessment of Ophthalmic and Visual Functioning using an Enjoyable Test and Stereoscopic Gaze Recording
Mr. T.G.M.F. Gorgels, PhD
PILOT – Towards treatment of glaucoma by a diet that bolsters mitochondrial function
Mr. Prof. R.O. Schlingemann, Prof., PhD, MD and Mrs. I. Klaassen, PhD
Novel targets in tip cells for anti-angiogenesis in exudative AMD
Mr. Prof. A.D.A. Paridaens, MD, PhD
PILOT – Towards a minimally invasive yet sufficient and safe orbital decompression in thyroid eye disease: a pilot cadaver study to compare three different techniques
Mr. Prof. Ir. R. Roepman, PhD
Improved human induced pluripotent stem cell (hiPSC)-derived model systems to assess disease mechanisms and treatment of retinal ciliopathies