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2009-2012

Second round (2009) – supported studies

Mrs. Prof. A. Rothova MD, PhD
Pathogenesis of Birdshot Chorrioretinopathy
Mrs. C.A.M. Bennebroek MD
Determination of Protein Profiles
Mrs. M.J. van Schooneveld MD, PhD
Studies of Families with RP & Stargardt Disease
Mrs M.J. Jager MD, PhD
Kinase-inhibitors for treatment of Uveal Melanoma
Mr. J. van der Steen, MD, PhD
Early Detection of Glaucoma
Mr. J. Wijnholds, PhD
Development of CRB1 Gene Therapy
Mrs. E.C. La Heij MD, PhD
Prediction of PVR Development
Mrs. A.I. den Hollander, PhD
Prediction of Treatment in Age-Related MD
Mr. Prof H.G. Lemij, MD, PhD
OTC for Glaucoma Diagnostics
Mr. Prof. F.P.M. Cremers, PhD
Autosomal Recessive Cone Dysfunction Disorders
Mrs. H. Kremer, PhD
RD in Usher Syndrome
Mr. Prof. R.O. Schlingemann, PhD, MD
Anti-angiogenesis Therapy in Age-Related MS
Mrs. Prof. C.C.W. Klaver, PhD, MD
Dissection of the Ethiology of Myopia

Third round (2010) – supported studies

Mrs. F.N. Boonstra, PhD
Causes of visual impairment and blindness in children in the Netherlands
Mrs. J.D.F. de Groot-Mijnes, PhD
Immune responses and oxidative stress in ARN
Mrs. Prof. A. Rothova, PhD, MD
Modification of ocular GVHD development by early local low-dose steroid application in patients after donor stem cell transplant
Mr. R. Florijn, PhD
PILOT – Implementatie van de ‘second generation’ sequencing methodologie in de oogheelkundige DNA diagnostiek
Mrs. M.J. Jager, PhD
Role of ischemia in metastasizing uveal melanoma
Mr. S. van der Stigchel, PhD
PILOT- De oogbewegingspatronen van patiënten met MD
Mr. Prof. F.P.M. Cremers, PhD
Elucidation of the molecular causes of arRP in the Netherlands
Mr. J.S.A.G. Schouten, PhD
Longitudinal outcome of medically treated patients with ocular hypertension or glaucoma
Mr. N. Jansonius, PhD
PILOT- De initiële behandeling van glaucoom – wat wil de patiënt?
Mr. H. Simonsz, PhD
Development and Clinical Validation of the DAISY
Mr. R.W.J. Collin, PhD
PILOT – Ontwikkelen van genetische therapie voor CEP290-geassocieerde LCA
Mrs. J.H. de Boer, PhD
Viral involvement in pathogenesis of pediatric uveitis
Mr. J.S.A.G. Schouten, PhD
An epidemiological study of major eye diseases, especially diabetic retinopathy, in 10.000 persons
Mr. J.R. Vingerling, PhD
OCT and Fundus Autofluorescence imaging of AMD in the general population

Fourth round (2011) – supported studies

Mr. J. Wijnholds, PhD
Functional integration of isolated retinal progenitor cells into the neural retina
Mr. Prof. P.M. van Hagen, PhD
The clinical importance of the neonatal Fc receptor in RPE
Mr. Prof. H.G. Lemij, PhD
Prediction of visual profnosis to optimize frequency of perimetric testing in glaucoma
Mrs. A.I. den Hollander, PhD
PILOT-Genetische oorzaken van complement activatie bij LMD
Mr. Prof. A.A.B. Bergen, PhD
Toward stam cell therapy for disorders of the retinal pigment epithelium (AMD)
Mr. T. Berendschot, PhD
PILOT – De invloed van luteine op de complement activatie bij LMD
Mrs. H.J.M. Beckers, PhD
PILOT – Risicofactoren voor glaucoom bij musici
Mrs. M.J. Jager, PhD
Inhibition of Placental Growth Factor (PlGF) in the Treatment of Uveal Melanomas
Mrs. M.J. Jager, PhD
PILOT – The role of aging in experimental glaucoma
Mr. Prof. R.O. Schlingemann, PhD, MD
The role of the angio-fibrotic switch in age-related macular degeneration
Mr. Prof. R.O. Schlingemann, PhD, MD
Mechanisms involved in neurite growth in epiretinal proliferations in proliferative diabetic retinopathy
Mrs. H. Kremer, PhD
PILOT – Ontwikkelen van genetische therapie voor USH2A-geassocieerde vormen van Usher syndroom en retinitis pigmentosa
Mr. Prof. C.B. Hoyng, PhD
Prediction model for the development of age-related macular degeneration
Mr. Prof. R.M.M.A. Nuijts, PhD
Corneal transplantation by ultra-thin DSAEK: thinner grafts, better vision?
Mr. H.J. Simonsz
Development and Clinical Validation of the Delft Assessment Instrument for Strabismus in Young Children (DAISY)
Mr. drs. A.C. Houtman
PILOT-The Stereotracker: towards Rescuing Binocular Vision in Infantile Esotropia
Mr. Prof. M. Kamermans, PhD
A Retinal Origin for Congenital Nystagmus
Mr. T.G.M.F. Gorgels, PhD
PILOT-Uitbreiding van de muizenoog- onderzoeksstraat met in vivo retinale celdood detectie en oogdrukmeting
Mrs. Prof. C.C.W. Klaver, PhD, MD
Identification of the genetic factors influencing myopia on chromosome 15q14
Mr. Prof. G.P.M. Luyten, PhD
Long-term follow up after implantation of Artisan Phakic Iris Claw Intraocular lens for the correction of high degree myopia
Mr. Prof. F.P.M. Cremers, PhD
Organisation, data management, and communication of RP5000: towards a comprehensive clinical and genetic analysis of inherited retinal dystrophies in the Netherlands

Fifth round (2012) – supported studies

Mrs. N.G. Tahzib, MD, PhD, FEBOphth
Applications and advantages of corneal crosslinking for treatment of keratoconus
Mr. G.L. Porro, PhD
Development of visual functions in children affected by brain diseases
Mr A.D.A. Paridaens, MD, PhD
PILOT – Moleculaire pathofysiologie van Graves’ opthalmopathie: op zoek naar nieuwe therapeutische mogelijkheden
Mrs. E.C. La Heij, MD, PhD, FEBOphth
Macular and retinal disease; anatomic and functional recovery after treatment
Mrs. Prof. A. Rothova, PhD, MD
PILOT – Evaluatie van innovatieve diagnostische technologieën op glasvocht voor de diagnose van intraoculair lymfoom
Mr. Prof. A. Kijlstra, PhD, FARVO
Effect of lutein on circulating biomarkers in age related macular degeneration
Mr. K.A. Vermeer, PhD
PILOT – ‘Public Rotterdam Ophthalmic Data’
Mr. J. Klooster, PhD
PILOT – Immunohistochemische analyse van gekweekte humane retina
Mr. Prof. R.O. Schlingemann, PhD, MD
Application of an in vitro BRB model to explore molecular mechanisms and mode of action of current therapeutics in macular edema
Mr. Prof. R.O. Schlingemann, PhD, MD
Molecular regulation of angiogenic tip cells in neovascular age-related macular degeneration
Mr. Prof. C.B. Hoyng, PhD, MD
Prediction model for the development of age-related macular degeneration
Mr. T.G.M.F. Gorgels, PhD
PILOT – Kosteneffectief genereren van AMD muismodellen met innovatieve Zinc-Finger Nuclease technologie
Mrs. M.J. van Schooneveld, PhD, MSc.
PILOT – Long-term clinical follow-up study of patients and families with choroideremia for future clinical trials
Mr. R.W.J. Collin, PhD
PILOT – Exoom sequencing in honden met progressieve retinale atrofie ter ontwikkeling van gentherapie voor netvliesdegeneratie
Mrs. A. van der Lelij, MD, PhD
PENTACON-trial: Partial ENdothelial Trepanation in Addition to anterior lamellar keratoplasty in keratoCONus patients. A multicenter randomized clinical trial
Mrs. F.N. Boonstra, PhD
Quantitative assessment of slow vision
Mr. N.M. Jansonius, MD, PhD
The Netherlands glaucoma study – Clinical data collection and DNA isolation
Mr. N.M. Jansonius, MD, PhD
PILOT – Laterale inhibitie in het netvlies: een verklaring voor onbegrepen licht- en donkeradaptatieproblemen bij mensen met glaucoom?
Mr. Prof. J.C. van Meurs
PILOT – Intravitreale of submacular injection van rtPA bij acute submaculaire bloeding
Mr. C.J.F. Boon, PhD
PILOT – Chronische retinitis centralis serosa: evaluatie van een prospectief klinisch behandelprotocol en genotype-fenotype correlatie
Mrs. J.D.F. de Groot-Mijnes, PhD
Immunopathogenesis of Parvovirus B19-associated uveitis with juvenile idiopathic arthritis
Mr. Prof. J.F. de Boer
PILOT – Detection and grading of Retinal Angiomatous Proliferation (RAP) using 1050 nm Doppler OCT
Mrs. Prof. N.E. Schalij-Delfos, PhD
Analysis of retinal oxygenation in retinopathy of prematurity
Mr. R. Roepman, PhD
Development of targeted therapies for retinal ciliopathies using patient-derived induced pluripotent stem cells
Mrs. L.I. van den Born, MD, PhD
Phenotyping of retinal dystrophies caused by mutations in the RPE65 and LRAT genes
Mrs. C.C.W. Klaver, PhD, MD
Development of refractive error and myopia in children
Mr. F.W. Cornelissen, PhD
Scherp zicht op het slechtziende brein: toepassing van een nieuwe functionele connectiviteitsmethode om corticale veranderingen samenhangend met gezichtsvelddefecten ten gevolge van retinale aandoeningen vast te stellen